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Naltrexone is one of three approved medications for AUDs. There are three ways to use naltrexone. Each of them has been researched and proven effective. The daily method, which is how it is most often prescribed, has the patient take the medication daily and attempt to abstain. The Sinclair Method has the patient take the pill one hour before the first drink, each and every time the person drinks. The third way is using Vivitrol, which is a monthly injection of naltrexone.