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Showing results for tags 'phenibut'.
TeetotalRecall posted a topic in Newbies NestCurrent high dose baclofen patient (140mg a day), who experienced great success (alcohol free, very little anxiety) for the first 7+ months, and then foolishly experimented with another GABAb agonist (phenibut) after losing a portion of my baclofen prescription. Though I was able to stop the other GABAb agonist by substituting it with baclofen, the dose I'd been at was no longer as effective. I titrated my baclofen use down to zero (with the aid of gabapentin to combat some of the anxiety I was experiencing), but only performed a baclofen drug holiday of 24 hours before resuming. In doing so,
[Disclaimer: I have some background in pharmacology, but I am not a medical doctor.] Hey everyone! What follows is information regarding the mechanism of action of baclofen as well as similar substances, their effect on anxiety, and my thoughts/implications. [I've decided to add elements of my personal story and current situation in the hopes that others can learn from my insights as well as my mistakes.] Baclofen's mechanism of action involves agonism of the GABAb receptor, as well as slight inhibition/attenuation of voltage-dependent calcium channels (VDCC). Some studies suggest th
Hi All, Hope everyone is doing well. Yesterday my order of Baclofen finally came in the mail! I was so excited to get it and decided to start it today. So, I've now been clear of alcohol for 9 days straight - which I'm pretty proud of. Anyway, during this time I've still been dosing phenibut daily- usually around 3-4 grams to maintain my sanity (this is a fairly high dose). On top of that I take a ton of herbs like passion flower, l-theanine and Valerian. I also use aniracetam- a nootropic for mood improvement and klonopin (although I've hardly touched it over the last week).